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An efficient method for the preparation of peptide alcohols
Journal article   Peer reviewed

An efficient method for the preparation of peptide alcohols

Alan Roy Katritzky, Nader Elmaghwry Abo-Dya, Srinivasa Rao Tala, Kapil Gyanda and Zakaria Kamel Abdel-Samii
Organic & biomolecular chemistry, Vol.7(21), pp.4444-4447
01/01/2009
DOI: https://doi.org/10.1039/b905730g
PMID: 19830293

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
N-Protected LL-dipeptide alcohols 3a-p, diastereomeric mixture (3d + 3d') and tripeptide alcohols 6a-c were synthesized by treatment of various amino alcohols with N-protected(alpha-aminoacyl)benzotriazoles 1a-c, 1f-m, (1a + 1a') and N-protected(alpha-dipeptidoyl) benzotriazoles 5a, 5b respectively in good yields with complete retention of chirality.

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