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An efficient one-pot synthesis of C-2-symmetric triazolophanes by copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction
Journal article   Peer reviewed

An efficient one-pot synthesis of C-2-symmetric triazolophanes by copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction

R. Rajesh, G. Periyasami and R. Raghunathan
Tetrahedron letters, Vol.51(14), pp.1896-1898
07/04/2010
DOI: https://doi.org/10.1016/j.tetlet.2010.02.020

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
A facile and efficient one-pot synthesis of 12-15-membered triazolophanes has been accomplished using CuAAC methodology. The formation of triazolophanes was confirmed by spectral analysis and the products were isolated in good yield. The effect of solvents on this reaction was also studied. (C) 2010 Elsevier Ltd. All rights reserved.

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