Sign in
An efficient synthesis of functionalised 2-(heteroaryl)-3H-benzo[f] chromen-3-ones and antibacterial evaluation
Journal article   Peer reviewed

An efficient synthesis of functionalised 2-(heteroaryl)-3H-benzo[f] chromen-3-ones and antibacterial evaluation

Sobhi M. Gomha and Hassan M. Abdel-Aziz
Journal of chemical research, Vol.37(5), pp.298-303
01/05/2013

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
An efficient synthesis of 19 2-(heteroaryl)-3H-benzo[f]chronnen-3-ones is described via reaction of 2-(3-hydroxyacryloyl)-3H-benzo[f]chromen-3-one with various heterocyclic amines and active methylene compounds. The synthesised compounds, 18 of which are novel, were characterised on the basis of their elemental analysis and spectral data. Eight of the synthesised products were evaluated as antibacterial agents.

Metrics

1 Record Views

Details