Abstract
In the present paper, we analyze a coupled system of nonlinear three point boundary value problems (BVPs) consisting of a coupled system of higher order hybrid sequential differential equations formulated by fractional operators. We study several new conditions in the direction of existence theory for solutions of the given hybrid system under the weaker hypotheses based on the method of measure of non-compactness in degree theory. The required conditions confirming the uniqueness and stability are derived in relation to the coupled system of hybrid sequential BVPs. Lastly, we extend our hybrid sequential system to a real mathematical model of typhoid treatment with four compartments and by deriving numerical schemes for this generalized hybrid sequential system, we analyze the variations of different fractional orders and their impact on dynamical behaviors of the mentioned hybrid system of typhoid model.(c) 2022 THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).