Abstract
Traditionally the aqueous extracts of dried roots of the plant
Ecbolium viride are used for menorrhagia, rheumatism and jaundice.
The aim was to evaluate the anti-inflammatory activity of
Ecbolium viride extract in an
in vivo model.
The ethyl acetate fraction of
Ecbolium viride root extract was prepared and administered orally to rats. The anti-inflammatory activity of
Ecbolium viride was determined by carrageenan-induced paw edema and cotton pellet granuloma models.
Oral administration of
Ecbolium viride extract reduced inflammation significantly (
P
<
0.01) in both the carageenan paw edema and the cotton pellet granuloma models.
The results of the study supported the traditional use of
Ecbolium viride in the treatment for inflammatory disease.