Abstract
The present research study was aimed to investigate the efficiency of selected medicinal plants against
Crude methanolic extracts from the seeds of leaves of
,
,
, and
were prepared. In addition, Atropine was also isolated from alkaloid components of
to evaluate their
anti-plasmodial effects. It was observed that proguanil (positive control) and Atropine displayed strong anti-plasmodial activity (94.04 and 68.02%, respectively) against
at 0.1 mg/mL concentration while the leaf extracts of other medicinal plants did not exhibit any notable anti-plasmodial activity. It was concluded that alkaloids of
plant’s extracts were rich in anti-plasmodial compound Atropine, which exhibit a remarkable anti-plasmodial activity against
. Anti-plasmodial action of medicinal plants are attributed to these phytochemicals.
studies using medicinal plant’s extracts and standardized methods will help to make more powerful and cost-effective anti-plasmodial compounds.