Abstract
Heterocyclic compounds play a vital role in the development of novel compounds because of their diverse pharmacological activities. Thiazine is a six-membered heterocyclic moiety. Various thiazine derivatives were synthesized or isolated from natural sources like plants and animals. Thiazine derivatives have varieties of pharmacological activities such as antimicrobial, antibacterial, antifungal, antiviral, anti-inflammatory, anticoagulant, anticancer, antihypertensive, and other useful biological as well as chemical applications. In the therapy of antimicrobial infections, new antimicrobial agents are needed because current antimicrobials have developed drug resistance. So, we discussed some thiazine derivatives, which exhibited antimicrobial activity.