Abstract
Forty-seven isolates of marine microorganisms were isolated from water, sediment and leaf litter, analyzed using the halo zones on cross streak plate assay, agar-overlay plate assay, agar diffusion method and Liquid (turbidity) assay in terms of their general inhibition effects to test bacteria (Campylobacter jejuni, Bacillus cereus, Pseudomonas. aeroginosa ATCC 15442, Salmonella enteric ATCC 13311 and Haemophilus infuenzae). The results demonstrated that most isolates are effective against pathogens bacteria. Based on biochemical and physiological properties, they were classified as Bacillus licheniformis KSAWD3. This isolate exerted board spectrum antibiotic activities against pathogenic bacteria when compared with the commercial antibiotics used in this study.