Abstract
Antimicrobial resistance among both Gram-negative and Gram-positive bacteria has been on the rise in the previous years. The presence of multidrug-resistant microorganisms has become a source of serious concern with regard to hospital-acquired infections. The most threatening and common multidrug-resistant pathogens have been grouped together under 'ESKAPE' acronym that stands for Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter spp. This study was conducted in Alkharj city to explore the antimicrobial resistance rate of ESKAPE Pathogens in 2017 and 2018. The data were extracted from the laboratory department after the ethical IRB committee approved the study. In this study, we found that ESKAPE pathogens cause nearly half the infections that were caused by bacteria and the most common ESKAPE pathogen was Klebsiella pneumonia, followed by Pseudomonas aeruginosa. Enterococcus faecium, Enterobacter. Pseudomonas aeruginosa and Klebsiella pneumonia were multidrug resistant. Acinetobacter baumannii bacteria were extensively drug resistance.