Abstract
Talbinah is a soup prepared from barley (Hordeum vulgare L.). The soup is named Talbinah for the reason that it is tinny and white. The main purposes of this research were determined antimicrobial and antimutagenicity action of Talbinah (Hordeum vulgare L.) extract. Dried Talbinah of 100 g were extracted with 80% methanol under agitation at room temperature. The consistent and reproducible results obtained using the standard disk diffusion technique showed that Talbinah extract exhibited strong antimicrobial potential. The strongest antimicrobial activity of extract was recorded against Staphylococcus aureus, and the lowest activity was observed against Candida albicans. The extracts showed both bacteriostatic and bactericide activities with MIC and MBC values found equal and ranged from 125 to 500 mu g/mL. At all the doses antimutagenic response was significant at (p < 0.01) against both the strains with a percent mutagenicity decrease from 40 to 25 for TA98 followed by TA100 with percent antimutagenicity from 30 to 11. The results of the study established that Talbinah is a better antimicrobial and antimutagenic agent.