Abstract
Extracellular gold nanoparticles mediated by Streptomyces tuirus DBZ39 were employed for their distinct characteristic properties and antimicrobial activities as a major objective of the present investigation. Defined size and distinct gold nanoparticles, obtained from biological sources in general and microbial sources in particular reveal spectacular biomedical applications. Scanning and Transmission Electron Micrographs, revealed the characteristic properties of extracellular gold nanoparticles in a controlled size of 24nm. X-ray diffraction analysis exhibits crystal phases of gold nanoparticles. Different materials including cotton, plastic and glass were used for coating with nanosolution and used to detect the antimicrobial activity against bacterial and fungal pathogens. An antimicrobial property of gold nanoparticles employing coated materials is a significant attribute. The antibacterial activity of gold nanoparticles was encouraging against gram negative bacterial pathogens E. coli and Pseudomonas aeruginosa, which can be explored further for their efficacy. The results suggest exploration of gold nanoparticles as a therapeutic agent in medical and pharmaceutical field.