Abstract
The present study was aimed to investigate antimicrobial potential of
Glycyrrhiza glabra roots. Antimycobacterial activity of
Glycyrrhiza glabra was found at 500
μg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both
Mycobacterium tuberculosis H
37Ra and H
37Rv strains at 29.16
μg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.