Abstract
Background: The present study aimed to screen shrimp shell, chitin and chitosan methanolic extract to display potent anti-bacterial and antioxidant potency in vitro for some recently used antioxidants as food supplements and in the form of pharmaceutical dosages.
Materials and methods: shrimp shell, chitosan and chitin methanolic extract have biological potency as antiracial antioxidant. The tested materials were determined through disc diffusion technique against three strains Gram-negative bacteria (Escherichia coli; Klebsiella pneumoniae and Pseudomonas aeruginosa) and four Gram-positive bacteria (Bacillus subtilis; Micrococcus luteus and MERSA). Their antioxidant activity was investigated with DPPH (2,2-diphenyl-1-picrylhydrazyl) to measure radical scavenging potency and suppression of linoleic acid peroxidation.
Results: The chitin extract possesses a high potency against the tested organisms than the chitosan and shrimp shell. The values are based on the DPPH (41.0 perpendicular to 1 mu g/ml). Chitin also shows an increase in the radical scavenging properties.
Conclusion: Data of the present study stated that shrimp shell, chitin and chitosan act as an antioxidant agent because they might carry free radical scavenging and cytoprotective activity.