Abstract
Malaria is an intraerythrocytic parasitic disease caused by the genus
of which
and
are the major species. The high cost and associated side effects of antimalarial drugs triggered research about medicinal plants to develop alternative and low-cost drugs with lesser side effects. Therefore, this study was designed to investigate the antiplasmodial activity of the
L’Hér. leaf extract against
and its phytochemicals in
. The methanolic extract of
was prepared and different concentrations of the crude extract and phytochemicals were used against
. The methanolic extract of
showed profound antiplasmodial activity (LD
0.084 mg/mL; 80.04%) at 0.1 mg/mL concentration after 24 h. Alkaloids, flavonoids, saponins, and tannins were found in the
methanolic extract. Only alkaloids at the concentration (0.1 mg/mL) exhibited 60.93% inhibition of
The methanolic extract of
exhibits antiplasmodial activity
. However,
efficacy is an important aspect in the testing of medicinal plants against parasitic infections and should be evaluated in future.