Abstract
(AG, Asteraceae) commonly called “nougd” in Arabic is traditionally used for the treatment of different gastrointestinal disorders. This study evaluates the effects of ethanol, chloroform and n-butanol extracts of AG on ulcerative colitis induced by various ulcerogens in rats and the isolation of new secondary metabolites. Ethanol extracts of the leaf of the AG demonstrated a powerful anti-ulcer activity which could be attributed to the synergistic effect of its constituents. Therefore, our results would be the first proof of traditional use of AG as an antiulcer ailment.