Abstract
Objective: To investigate the application value of anterior cervical zero-profile interbody fusion device (Zero-P) on anterior cervical decompression and bone fusion, by comparing the effect differences of Zero-P and anterior ceryical plate cage benezech (PCB) in treating cervical spondylopathy. Methods: 120 patients with cervical spondylopathy (from February 2014 to January 2016) were selected and randomly divided into experimental group and control group of 60 cases in each. Experimental group performed operation with Zero-P while control group with PCB. The outcomes, such as operation time and intraoperative hemorrhage volume, the time of bone graft fusion, Japanese Orthopaedic Association (JOA) score, visual analogue scale (VAS), Neck Disabilitv Index (NDI), short form 36 questionnaire (SF-36), cervical curvature (Cobb angle) were compared between these two groups. Results: In the experimental group, the excellent rate of curative effect in final follow-up visit was 93.3%, which was significantly higher than that of control group (80%) (P=0.029). 18.3% patients in the experimental group presented with postoperative dysphagia, which was obviously lower than that of control group (28.3%) (P=0.001). Besides, operation time and intraoperative hemorrhage volume in the experimental group were also significantly lower than those of control group (P=0.000, P=0.001). After treatment, the improvements of JOA, VAS score and NDI in the experimental group were significantly better than control group (P=0.000, P=0.000, P=0.000). And there were no significant differences between two groups in SF-36, the time of bone graft fusion and Cobb angle (P=0.368, P=0.563, P=0.452). Conclusion: Zero-P, with a simple operative procedure and low incidence of postoperative dysphagia, had a better curative effect in treating cervical spondylopathy. And it could effectively improve of cervical curvature, making the early clinical efficacy satisfactory.