Abstract
Surgical site infections are responsible for more than 20% of these infections, and it is the most frequent Health care-related infections in middle-income and low-income countries. There is a lack in studying of antibiotics use for surgical prophylaxis in Alkharj. Therefore, this study aims to assess the appropriateness of surgical antimicrobial prophylaxis practices in a public hospital in Alkharj. The study includes 2 parts; the first part includes a retrospective analysis of medical records and the second parts included a structured review with the physicians. The result of the present study shows that there is a problem in choosing the appropriate antibiotics for surgical prophylaxis in the hospital. Furthermore, the duration of antibiotic use in the hospital was largely inappropriate. It is important to start antimicrobial stewardship programs to promote safe and effective use of antimicrobials and to increase the surgeon awareness regarding the antibiotic use.