Abstract
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•Aptameric nanobiosensors is an affinity-based nanosensors interfaced with aptamers.•It is a rapid and sensitive diagnostic platform for the detection of SARS-CoV-2.•Detection limit of these apta-nanobiosensors vary from pM to fM concentrations.•Careful selection of aptamers and signal transducers is critical for better results.
COVID-19 pandemic has left a catastrophic effect on the world economy and human civilization. As an effective step towards controlling the transmission of viral infections during multiple waves of COVID-19, there is an urgent need to develop robust nanobiosensors for the detection of SARS-CoV-2 with high sensitivity, specificity, and fast analysis. Aptameric nanobiosensors are rapid and sensitive diagnostic platforms, capable of SARS-CoV-2 detection, which overcomes the limitations of the conventional techniques. This review article presents an outline of the aptameric nanobiosensors established for improved diagnosis of SARS-CoV-2 and the future perspectives are also covered.