Abstract
The study was aimed at investigating the biologically active compounds in Pleurotus sajor-caju wild edible mushroom and its potential antioxidant and antibacterial activity against multidrug-resistant (MDR) Salmonella typhi (Accession No. KT037135). Gas chromatography-mass spectrometry (GC-MS) and Fourier transform infrared spectroscopy (FT-IR) analysis exposed the presence of bioactive components. The antioxidant properties were evaluated using the free radical scavenging method 1,1-diphenyl-2-picrylhydrazyl (DPPH). The methanolic extract of the P. sajor-caju was exhibited 67.42 +/- 0.25% of antioxidant activity according to the DPPH. The bactericidal activity was evaluated and the results showed that the S. typhi growth was considerably decreased in a dose-dependent approach. Thus, it is recommended that the methanolic extract of the P. sajor-caju could be a lead drug and chosen to very good antioxidant activity and also effectively control the MDR S. typhi.