Abstract
iHeart is a mobile healthcare system which monitors and tracks patients with hypertension and arrhythmia. This empirical study aims to assess the interaction between human and iHeart. In line with this, a survey was conducted among healthcare professional in two cities of Isfahan and Penang to find how intention to "Use" of iHeart and "User satisfaction" conveys the role of effective factors [Information Quality (IQ), Service Quality (SQ), System Quality (SysQ), Trust (Tr), Anxiety (Ax), and mHealth Literacy (mHL)] to the "Success of Human Interaction (SHI)" with iHeart. The total number of 323 respondents returned the questionnaire. Using DeLone and McLean IS success model, a conceptual model was developed to identify the mediating effects of "Use" and "User satisfaction". Covariance-based structural equation modelling was applied for data analysis using the statistical software AMOS. In this study, mediation effect was examined in three different methods including Baron and Kenny, Sobel test, and Bootstrapping technique. The most reliable results are from bootstrapping technique, which indicate that "Use" mediates the effects of SysQ, Tr, and mHL on SHI. In addition, "User satisfaction" is a mediator between SysQ, SQ, and mHL with SHI. Ultimately, IQ has direct effect on SHI without involvement of mediator.