Abstract
Introduction: Glycated Hemoglobin (HbA1c) and Fasting Blood Glucose (FBG) measurements provide useful information about glycemic control status in diabetic patients. Estimated Average blood Glucose (eAG) is often calculated to translate HbA1c result into terms that closely represent a daily reading of Fasting Blood Glucose (FBG). Objective: This study was carried out to evaluate the glycemic control status and the association between FBG and eAG in diabetic patients. Methods: This retrospective cohort study was conducted on FBG, HbA1c tests results of 687 diabetic patients (324 males and 363 females) who were attending the diabetic care center in Khartoum state. HbA1c level >7% represents the cutoff for poor glycemic control as well, fasting blood glucose levels of (<130 mg/dl, 130-180 mg/dl, and >180 mg/dl) were used to categorize the patients into three subgroups of glycemic status (A, B and C) respectively. (eAG) was calculated by using the regression equation: eAG (mg/dL)=28.7 x HbA1c (NGSP, %)-46.7. Results: The rate of poor glycemic control was found to be 76.9%, 80.6% for males, and 73.6% for females. A positive significant correlation was observed between FBG and eAG within the study groups (p<0.001) while for the subgroups the association was found significantly different only in the more poor glycemic control group C (p=0.369, p<0.001). Conclusion: Calculation of estimated average blood glucose with fasting blood glucose help patients and clinicians in assessment of glycemic control status.