Abstract
OBJECTIVE: We designed this systematic review to summarize the diabetes -re-lated glaucoma articles produced from 2011 to 2022. We further aimed to perform a meta -anal-ysis to determine the vital association between these two parameters.MATERIALS AND METHODS: Data sources like PubMed, MEDLINE, and EMBASE were used to find the relevant research. Reviews, case re-ports, and editorial letters were excluded. Arti-cles inspection was conducted by the main au-thor who extracted the study title and abstract in the first screening by using keywords to find the eligible articles. Heterogeneity was accessed by using the Cochrane Q test and I2test.RESULTS: 10 studies were reported with 2,702,136 cases of diabetes. Out of these, 64,998 incidents of glaucoma were observed. The pooled prevalence of diabetic retinopathy was 11.7% as-sociated with glaucoma. A significant I2 value was achieved (100%) with Cochran's Q of 183.6.CONCLUSIONS: In conclusion, we found di-abetes duration, elevated IOP, and fasting glu-cose levels are one of the leading risk factors for glaucoma. Fasting glucose levels and diabe-tes are also major contributors to elevated IOP levels.