Abstract
Chiral bicyclic guanidine catalyzes the asymmetric H-D exchange reactions. Up to 30% ee was achieved. DFT calculations were employed to elucidate and explain the origin of the reaction's stereoselectivity.
- Title
- Asymmetric H-D exchange reactions of fluorinated aromatic ketones
- Creators - without role
- Yujun Zhao - National University of SingaporeXiaozhi Lim - King Abdullah University of Science and TechnologyYuanhang Pan - National University of SingaporeLili Zong - National University of SingaporeWei Feng - Duke-NUS Medical SchoolChoon-Hong Tan - National University of SingaporeKuo-Wei Huang - King Abdullah University of Science and Technology
- Publication Details
- Chemical communications (Cambridge, England), Vol.48(44), pp.5479-5481
- Publisher
- Royal Soc Chemistry
- Number of pages
- 3
- Grant note
- National University of Singapore King Abdullah University of Science and Technology; King Abdullah University of Science & Technology
- Identifiers
- 9942796008331
- Academic Unit
- King Abdullah University of Science & Technology
- Language
- English
- Resource Type
- Journal article