Abstract
Root extracts of Euphorbia wallichii obtained from n-hexane (E1), chloroform (E2), ethyl acetate (E3) and n-butanol (E4) were tested hi vitro for their phytotoxicity, cytotoxicity, antibacterial and antifungal activities. All the extracts at high concentration of 1000 mu g ml-1 showed 60-100% phytotoxicity and 50-100% cytotoxicity while at low concentration of 10 mu g ml-1 they showed 30-80% phytotoxicity and 25-70% cytotoxicity. Antibacterial study performed against six bacteria viz., Escherichia coli, Bacillus subtilis, Shigella flexenari, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhi showed a trend of inhibition zone in E2 and E3 extracts was found to be the most active while E1 and E4 extracts exhibited moderate to low activity in killing the tested bacteria. No significant antifungal activity tor 6 tested fungi was observed.