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BN nanospheres as CpG ODN carriers for activation of toll-like receptor 9
Journal article   Peer reviewed

BN nanospheres as CpG ODN carriers for activation of toll-like receptor 9

Chunyi Zhi, Wenjun Meng, Tomohiko Yamazaki, Yoshio Bando, Dmitri Golberg, Chengchun Tang and Nobutaka Hanagata
Journal of materials chemistry, Vol.21(14), pp.5219-5222
01/01/2011
DOI: https://doi.org/10.1039/c1jm10199d

Abstract

Chemistry Chemistry, Physical Materials Science Materials Science, Multidisciplinary Physical Sciences Science & Technology Technology
For the first time, we demonstrated BN nanospheres (BNNSs) can interact with biomolecules and deliver unmethylated cytosine-phosphate-guanine oligodeoxynucleotides (CpG ODNs) into cells to activate toll-like receptor 9 (TLR9), which is a very important process for therapy of cancers and allergy diseases.

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