Abstract
Forty two normal male albino rats of Sprague Dawley strain, weighing (170 +/- 5 g) strain were fed on high fat diet for six week to induce obesity. The obesity rats were randomly classified into six groups (7 rats each) and treated with orlistat, coffee, green tea, cinnamon and mixture of them for six week.
The results revealed that, obese rat groups which treated with orlistate, green tea, coffee, cinnamon and mixture of them showed lowered values of final weight, weight gain, gain percent, FER, leptin, glucose, cholesterol, total lipids, phospholipids, triglyceride, LDL-C, VDL-C and cholesterol/HDL-c but a significant increase in the value of serum HDL-C in comparing with control (+ve). The rat group which treated with orlistat showed non significant difference in the values of serum AST, ALT & ALP but all rat groups treated with green tea, coffee, cinnamon and mixture of them showed a significant decrease in serum AST, ALT & ALP, serum creatinine and urea compared with control (+ve).
The rat groups which treated with green tea, coffee, cinnamon and mixture of them showed a significant decrease in the values of serum creatinine and urea but the rat groups which treated with cinnamon and mixture of green tea, coffee and cinnamon showed a significant decrease in the value of serum uric acid compared with control (+ve). [Hala, E.M El- Kewawy, Farida, Abdullah Al-Firdous and Rasha M Nagib. Beneficial Effects of some beverage consumption and Orlist drug on Diet Induced Obesity in Experimental Rate. Life Science Journal. 2011;8(2):667-675] (ISSN:1097-8135). http://www.lifesciencesite.com.