Abstract
Ethylidene hydrazine (4a,b) and thiazolidin-4-one (5) derivatives were synthesized by the reaction of ethylidenethiosemicarbazide derivative (3a) with ?-haloketone/ethyl bromoacetate, respectively. Hetrocyclization of ethylideneacetohydrazide derivative (7) with o-phenolic aldehydes gave the corresponding coumarin derivatives (8,9). The interaction of 7 with acetylacetone afforded the corresponding pyridine derivative (10). Treatment of the arylidene derivative 11b with malononitrile afforded the corresponding pyran derivative (12). The new products 3-12 were subjected to IR, 1H NMR and mass spectra studies.
Derivati etilidenhidrazina (4a,b) i tiazolidin-4-ona (5) sintetizovani su u reakciji derivata etilidentiosemikarbazida (3a) sa ?-haloketonom odnosno etilbromoacetatom. Hetrociklizacija derivata etilidenacetohidrazida (7) sa o-fenolnim aldehidima daje odgovarajuce kumarinske derivate (8, 9). Interakcija 7 sa acetilacetonima dala je odgovarajuci derivat piridina (10). Tretiranje ariliden-derivata 11b sa malononitrilom dala je odgovarajuci derivat pirana (12). Struktura novih produkata 3-12 proucavana je preko IR, 1 H NMR i masenih spektara.