Abstract
We report edible mushroom extract (EVIL) as a robust and environmentally friendly precursor for the biogenic synthesis of selenium nanoparticles (SeNPs). The as-synthesized SeNPs were characterized by UV-visible spectrophotometer (UV-vis) Fourier-transform infrared spectroscopy (FTIR) Transmission electron microscope (TEM) and Dynamic light scattering (DES)techniques, The results obtained from TEM and DLS suggested that the SeNPs synthesized with EME are in the size of similar to 8 nm with a spherical shape and monodispersity. The occurrence of antioxidants in the EVIE has been confirmed with FTIR and thereby confirmed that flavonoids and phenolic compounds played a pivotal role in the biosynthesis of SeNPs from Na2SeO3. In addition EME-SeNPs cytotoxicity cytotoxicity on the cell lines of prostate cancer (PC-3) at concentrations ranging from 0.5-1.5 mu M. At a concentration of 0.25 MM against 1,1-diphenyl-2-picrylhydrazyl the average scavenging level of EME-SeNPs was found to be > 80.20 %, Moreover the percentage viability of gram-negative E.coli and gram-positive E.faccium was recorded at a high concentration of EME-SeNPs and found to be 82% and 65 %. respectively.