Abstract
Thermal and biological studies of three heterometallic Mn-Ln polynuclear complexes (1-3) having general formula [MnIII2Ln3(nbdeaH)3(nbdea)2(piv)8].MeCN, where bdeaH2 = N-butyldiethanolamine, piv = pivalate, Ln = Dy (1), Er (2) and Y (3) were done. The antioxidant activity of different hetero-metallic compounds was evaluated by 1,1-Diphenyl-2-picrylhydrazyl (DPPH) and enzyme inhibition studies were tested on acetylcholinestrase (AChE), butylcholinestrase (BChE), lipoxygenases (LOX) and tyrosinase. All complexes have shown low antioxidant activity while these complexes were showed significant activity against AChE and BChE. Moreover, complexes (1-3) showed low activities against the LOX and the tyrosinase. Thermal stability of these complexes was also studied and the thermal decomposition of compounds was interpreted in term of its structure and the end product was found to be metal oxide.