Abstract
Fungi is a diverse group of microorganisms with over 1.5 million species worldwide. It lives in a variety of environments and develops a variety of survival mechanisms that allow it to manufacture a wide variety of chemicals, i.e., biomolecules. Organic acids, enzymes and secondary metabolites have been shown to be useful in the production of biomolecules. They may be used in a broad range of fields, including pharmaceutical research, agricultural and food biotechnology, commodities biochemicals, agri-foods, chemical engineering, diagnostics, medicines, and medical device development. It also explores fungal macromolecules' health and healing properties, regulates phytohormone synthesis or breakdown in plant roots, improves hormone production, and supports bio-stimulant composition. There are a variety of antimicrobial/antifungal biomolecules in agriculture that may be employed to minimize crop yield-reducing pest and diseases. These biomolecules, which are useful in both the pharmaceutical and agricultural industries, are the focus of this review.
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•Fungal bioproducts for sustainable pharmaceutical applications.•Fungal biomolecules against cardiovascular, diabetes, reproductive, cancer, and neurodegenerative diseases.•Biomolecules of fungi as antidote for malnutrition and related diseases.•Metabolic engineering for the advent of new bioactive compounds.