Abstract
Bacteriocins have been described as antimicrobial compounds that are produced by bacteria. Immobilized cell technology has been successfully improved the enzymes thermal stability, to stand the temperature used in food industries and still active. In this work, Lactic Acid Bacteria (LAB) Leuconostoc mesentroides was isolated from muscle of the domestic goat from Jeddah-Saudi Arabia, and immobilization on different materials like glass wool, cork, Sodium alginate, Linen fibers and polyurethane foam. The immobilization of the bacteria on alginate has shown the highest antimicrobial activity of the enzyme. Effect of different number of bead as inoculum size on bacteriocin production also tested. The immobilization of LAB on alginate has shown better results for repeated use of bacteria for successive eight times with retention of over 85% of the bacteriocins activity as compared to complete loss of activity and disruption of the control. It concluded that, the immobilization of LAB on alginate has shown better results for enhancement the production of bacteriocin.