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Bis-Hydrazonoyl chloride as precursors for synthesis of novel polysubstituted bis-azoles
Journal article   Open access  Peer reviewed

Bis-Hydrazonoyl chloride as precursors for synthesis of novel polysubstituted bis-azoles

Nabila Abdelshafy Kheder and Thoraya Abdel Reheem Farghaly
Arabian journal of chemistry, Vol.10, pp.S3007-S3014
05/2017
DOI: https://doi.org/10.1016/j.arabjc.2013.11.040

Abstract

Anticancer activity Antimicrobial activity bis-Hydrazonoyl chloride bis-Pyrazoles Nucleophilic addition reaction
A series of novel bis-pyrazole, bis(imidazo[1,2-b][1,2,4]triazole) and bis(imidazo[1,2-a]benzimidazole) derivatives were synthesized via bis-hydrazonoyl chloride. Structures of the synthesized compounds were elucidated by means of IR, 1H NMR and mass spectral data. The biological activity of the newly synthesized compounds was examined and some of them were found to possess antimicrobial and anticancer activities.
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https://doi.org/10.1016/j.arabjc.2013.11.040View
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