Abstract
Infectious diseases a curse for humanity can be curbed through immunization. Vaccination can make people more resilient toward infectious diseases and the safety of the vaccine is of prime importance for public health. A smart vaccine management system can address the issue of vaccine expiration and counterfeiting. The study was conducted in twofolds: Stage I, a quantitative cross-sectional survey design was deployed to understand stakeholder adoption intention (ADI) toward blockchain-enabled vaccine supply chain through extended technology adoption model using partial least square structural equation modeling. Findings entail stakeholders' trust and perceived ease of use for blockchain-enabled vaccine supply chain directly affect perceived usefulness (PUS) and individual subjective norm. PUS significantly influences the ADI of stakeholders toward blockchain in the vaccine supply chain. Stage II, a blockchain integrated vaccine supply chain architecture with Internet of things devices was proposed to bring transparency and flexibility to the vaccine supply chain. Architecture would benefit the beneficiary to approve or disapprove the vaccines through the self-generated report and medical health centers can see the efficacy of vaccines before clinical delivery to patients.