Abstract
In this work, gold nanoparticles irradiated with nanosecond short pulse laser for breast cancer treatment is studied theoretically. Nanophotolysis is involved for selective damaging of breast cancer cells. Results shows that laser fluence of 1.5 J/cm(2) interact with gold nanoparticles and generates a maximum number of ions. Laser light in the visible region interacts with the gold foil. At 700 nm, 12 x 10(12) ions are produced for the laser intensity of 8.89 x 10(7) W/cm(2). Slow increase in the Coulomb explosion pressure from 0.6 x 10(6) Pa to 2 x 10(6) Pa is observed for a cluster size of range 10 nm to 20 nm. Penetration of nanobullets in tumor increases with the increase of temperature from 39.83 degrees C to 62.20 degrees C. Number of cell damaged increases by increasing the number of ions (6 x 10(16) cells are damaged by 9.59 x 10(20) gold ions). Findings are compared with the other experimental results and are found in excellent agreement. It is concluded from current work that nanophotolysis therapy is may be useful in future for selective damaging of breast cancer cells.