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Bronsted Acid Catalyzed Reductive Amination with Benzothiazoline as a Highly Efficient Hydrogen Donor
Journal article   Peer reviewed

Bronsted Acid Catalyzed Reductive Amination with Benzothiazoline as a Highly Efficient Hydrogen Donor

Chen Zhu and Takahiko Akiyama
Synlett, Vol.2011(9), pp.1251-1254
01/06/2011
DOI: https://doi.org/10.1055/s-0030-1260539

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Reductive amination of aldehyde and amine proceeded smoothly in the presence of benzothiazoline as efficient hydrogen source by means of 20 mol% trifluoroacetic acid to give the corresponding amines in excellent yields. Hydrogen-donor abilities of benzothiazoline, benzimidazoline, and benzoxazoline were compared.

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