Abstract
The goal of this review was to provide evidence-based referrals for the therapy and avoidance of contact and atopic dermatitis. We conducted computerized search among electronic databases; EMBASE, COCHRANE and MEDLINE for literature available in the databases to the end of 2018, using the following search term including variants: "Contact dermatitis", "atopic dermatitis", "Management", "treatment". Atopic dermatitis (AD) is a chronic and relapsing illness influencing an enhancing variety of patients. Normally starting in very early youth, AD can be the first action of the so-called atopic march, i.e. followed by allergic rhinitis and allergic asthma. AD is a paradigmatic genetically intricate disorder including gene-gene and gene-environment interactions. The major treatment-goals include the removal of inflammation and infection, protecting and restoring the barrier function and managing worsening variables. The general future strategy in AD will certainly be aimed to regulate skin inflammation by a more proactive management in order to possibly avoid the appearance of sensitization in addition to develop personalized management based upon genetic and pathophysiologic info.