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CRISPR-TSKO: A Tool for Tissue-Specific Genome Editing in Plants
Journal article   Peer reviewed

CRISPR-TSKO: A Tool for Tissue-Specific Genome Editing in Plants

Zahir Ali, Magdy M Mahfouz and Shahid Mansoor
Trends in plant science, Vol.25(2), pp.123-126
02/2020
DOI: https://doi.org/10.1016/j.tplants.2019.12.002
PMID: 31859038

Abstract

Arabidopsis Clustered Regularly Interspaced Short Palindromic Repeats CRISPR-Cas Systems Gene Editing Mutagenesis
Functional genomics is at the core of studying the exact function of genes. However, homozygous knockouts of essential and pleiotropic effectors (almost 10% of the genome) are not always possible, thus, functions of these genes remain obscured. The tissue-specific genome editing tool (CRISPR-TSKO) recently described by Decaestecker et al., can characterize these indispensable genes and has wide applications in plants.

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