CRISPR/Cas13 as a Tool for RNA Interference

Zahir Ali; Ahmed Mahas; Magdy Mahfouz

doi:10.1016/j.tplants.2018.03.003

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CRISPR/Cas13 as a Tool for RNA Interference

Journal article

Peer reviewed

CRISPR/Cas13 as a Tool for RNA Interference

Zahir Ali, Ahmed Mahas and Magdy Mahfouz

Trends in plant science, Vol.23(5), pp.374-378

01/05/2018

DOI: https://doi.org/10.1016/j.tplants.2018.03.003

PMID: 29605099

Abstract

Life Sciences & Biomedicine

Plant Sciences

Science & Technology

Almost all biological processes involve RNA, making it crucial to develop tools for manipulation of the transcriptome. The bacterial CRISPR/Cas13 system was recently rewired to facilitate RNA manipulation in eukaryotes, including plants. We discuss here the opportunities and limitations of using CRISPR/Cas13 in plants for various types of RNA manipulation.

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Title: CRISPR/Cas13 as a Tool for RNA Interference
Creators - without role: Zahir Ali - King Abdullah University of Science and Technology
Ahmed Mahas - King Abdullah University of Science and Technology
Magdy Mahfouz - King Abdullah University of Science and Technology
Publication Details: Trends in plant science, Vol.23(5), pp.374-378
Publisher: Elsevier
Number of pages: 6
Grant note: OSR-2015-CRG4-2647 / King Abdullah University of Science and Technology (KAUST); King Abdullah University of Science & Technology OSR-2015-CRG4-2647 / Office of Sponsored Research (OSR)
Identifiers: 9942180708331
Academic Unit: King Abdullah University of Science & Technology
Language: English
Resource Type: Journal article