Cancer-related mutations in BRCA1-BRCT cause long-range structural changes in protein-protein binding sites: A molecular dynamics study

Journal article

Peer reviewed

Craig A. Gough, Takashi Gojobori and Tadashi Imanishi

Proteins, structure, function, and bioinformatics, Vol.66(1), pp.69-86

01/2007

PMID: 17063491

Abstract

binding entropy

breast cancer

disease mutations

protein-protein interactions

quasiharmonic analysis

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Title: Cancer-related mutations in BRCA1-BRCT cause long-range structural changes in protein-protein binding sites: A molecular dynamics study
Creators - without role: Craig A. Gough - Japan Biological Informatics Consortium
Takashi Gojobori - National Institute of Genetics
Tadashi Imanishi - National Institute of Advanced Industrial Science and Technology
Publication Details: Proteins, structure, function, and bioinformatics, Vol.66(1), pp.69-86
Publisher: Wiley Subscription Services, Inc., A Wiley Company
Number of pages: 18
Identifiers: 9943235908331
Academic Unit: King Abdullah University of Science & Technology
Language: English
Resource Type: Journal article