Candida antarctica lipase B-catalyzed synthesis of acetamides using [BMIm(PF 6)] as a reaction medium

Kishor P. Dhake; Ziyauddin S. Qureshi; Rekha S. Singhal; Bhalchandra M. Bhanage

doi:10.1016/j.tetlet.2009.03.170

Back

Candida antarctica lipase B-catalyzed synthesis of acetamides using [BMIm(PF 6)] as a reaction medium

Journal article

Peer reviewed

Candida antarctica lipase B-catalyzed synthesis of acetamides using [BMIm(PF 6)] as a reaction medium

Kishor P. Dhake, Ziyauddin S. Qureshi, Rekha S. Singhal and Bhalchandra M. Bhanage

Tetrahedron letters, Vol.50(23), pp.2811-2814

10/06/2009

DOI: https://doi.org/10.1016/j.tetlet.2009.03.170

Abstract

Acetamide-synthesis

Amidation

Candida antarctica lipase B (CaL B)

Enzymatic synthesis

Ionic liquids

An efficient protocol has been developed for synthesis of acetamides using Candida antarctica lipase B (CaL B) in [BMIm(PF 6)] as a greener reaction medium. An efficient protocol has been developed for synthesis of acetamides using Candida antarctica lipase B (CaL B) in [BMIm(PF 6)] as a greener reaction medium. The reaction is applicable to a wide variety of aliphatic esters/acetic acid and amines providing excellent yields of corresponding acetamide. The catalyst exhibits remarkable activity and is reusable for up to four consecutive cycles.

Metrics

1 Record Views

Details

Title: Candida antarctica lipase B-catalyzed synthesis of acetamides using [BMIm(PF 6)] as a reaction medium
Creators - without role: Kishor P. Dhake - Institute of Chemical Technology
Ziyauddin S. Qureshi - Institute of Chemical Technology
Rekha S. Singhal - Institute of Chemical Technology
Bhalchandra M. Bhanage - Institute of Chemical Technology
Publication Details: Tetrahedron letters, Vol.50(23), pp.2811-2814
Publisher: Elsevier Ltd
Identifiers: 9941924408331
Academic Unit: King Fahd University of Petroleum & Minerals; King Abdullah University of Science & Technology
Language: English
Resource Type: Journal article