Abstract
Chili peppers are commonly used around the world to make a desirable taste for food, particularly fast food like spicy chicken. Studies indicate that red chili pepper makes some alterations in liver enzymes and lipid profiles. The goal of this study was to see how hypercholesterolemic rats changed their lipid profiles (Cholesterol, Triglycerides, HDL, VLDL, LDL) as well as some liver enzymes (ALP, GPT, and GOT) were evaluated in hypercholesterolemic rats. Thirty-five male rats were separated into seven groups, each with the same number of rats. First group was treated as a control negative group with no changes, while the other six groups were fed an extra 2% cholesterol for two weeks to induce hypercholesterolemia. Then there are two hypercholesterolemic groups were fed different doses of red chili pepper (RCP) extract (10, 20 and 40 mg/kg body weight (B.Wt.)), two were fed 30% (fried chicken and chicken burgers), and one remained on standard diet only (control positive). The impact of RCP on liver function and alterations in lipid profiles was investigated. The oral dose of 2% cholesterol for two weeks caused hypercholesterolemia in rats, according to our findings. The findings suggested that taking enough RCP orally as part of a standard/healthy diet or as a fast food component improves lipid profiles and liver function test values.