Abstract
High frequency ultrasound is one of the primary imaging modalities for diagnosis of thyroid nodules, unfortunately there is limitation of ultrasound in differentiating benign from malignant nodule, fine needle aspiration (FNA) is required to differentiate benign and malignant thyroid nodules. This was a prospective study conducted in King Fahad Specialist Hospital in Dammam (Kingdom Saudi Arabia), in the period from February 2020 to February 2021, the main aim of the study to characterize thyroid nodules using high frequency ultrasound and to correlate sonographic features with the FNA results. The data collected from 222 patients with clinically suspected thyroid nodule, after taken a written Hospital in Dammam; RAD0317, then verbal consent was taken from all patients, then analyzed by SPSS version 23. The study showed that thyroid nodules occur commonly in females 76.6%, on FNA results 51.4% are benign. On high frequency ultrasound the malignant nodules are mostly hypoechoic, wider than taller, with presence of macrocalcification, moderate or severe vascularity in Doppler interrogation, while benign nodules are commonly seen as hypoechoic or isoechoic, wider than taller, with no or macrocalcification and a vascular or with mild peripheral vascularity in Doppler. Strong significant difference was found in sonographic features for benign and malignant nodules, P<0.01 except for composition of nodule. The study concluded that there is strong significant difference in sonographic features of benign and malignant nodules except for composition of nodule.