Abstract
Pipemidic acid is one of an efficient quinolone antibacterial drug. Thecomplexitybetween pipemidic acid "Hpipc" withgallium (III) germanium (IV) and silicon(IV) afforded three molecular formulas of [Ga(pipc)(2)(H2O)(Cl)]center dot 4H(2)O, [Ge(pipc)(2)(Cl)(2)] center dot 4H(2)O, 2 and[Si(pipc)(2)(Cl)(2)] center dot 4H(2)O, 3 complexes. These three new complexes were characterized based on elemental analysis, conductance, FTIR, UV-Vis, (HNMR)-H-1 and XRD spectroscopy. The pipc chelate exhibits O, O coordinated through the carbonyl (C=O) and carboxylato (COO) of both oxygen atoms. Six coordinate geometry was proposed regarding complexes of 2 and 3, so the axial position was occupied by two coordinated chlorideatoms. In vitro, the antibacterial, antifungal, and anti-cancer assessments concerning the synthesized pipc complexes were scanned. These complexes have an excellent anti-microbial activity.