Abstract
The volatile oil obtained by hydro-distillation of matured peels of Citrus reticulata and leaves of Murraya koenigii, belonging to the family Rutacea were subjected to GC-MS analysis for their chemical characterization. Major components were found to be Limonene (92.83%) in C. reticulata and Eugenol (81.61%) in M. koenigii. Both oils showed good antioxidant activity by scavenging DPPH radical (IC50 = 24.77 and 26.68 mu g/ml) and inhibiting linoleic acid (70.33 and 82.78 %) for both C. reticulata and M. koenigii, respectively. Antimicrobial activity of oils was accomplished using disc diffusion method followed by minimum inhibitory concentration (MIC) against various pathogenic bacteria and fungi. Fungal strains were found to be more sensitive against both of the oils. Minimum hemolysis (0.08 & 0.34%) was observed at 0.5 mg/mlin case of M. koenigii against both human and bovine erythrocytes, respectively.