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Chiral peptide nucleic acid monomers (PNAM) with modified backbones
Journal article   Peer reviewed

Chiral peptide nucleic acid monomers (PNAM) with modified backbones

Alan Roy Katritzky and Tamari Narindoshvili
Organic & biomolecular chemistry, Vol.6(17), pp.3171-3176
07/09/2008
PMID: 18698477

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Convenient high yielding syntheses of optically pure PNAMs comprising L- or D-serine, L-lysine and L-arginine units linked to thymine or Cbz-cytosine are described. Simple workup and inexpensive reagents arc employed and free amino acids are used as coupling components.

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