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Cholesterol esterification by transacylation in human and experimental atheromatous lesions
Journal article

Cholesterol esterification by transacylation in human and experimental atheromatous lesions

Y.H. Abdulla, C.C. Orton and C.W.M. Adams
Journal of atherosclerosis research, Vol.8(6), pp.967-973
11/1968
PMID: 5707802

Abstract

In vitro cholesterol esterification by either human or rabbit’s aorta in the presence of β-fatty acid-labelled lecithin appears to depend on a lecithin:cholesterol fatty acid (acyl) transferase. The activity of this enzyme increases in human fatty atherosclerotic lesions and in atherosclerotic aortas from cholesterol-fed rabbits. Activity decreases in fibrous and calcified human atherosclerotic lesions.

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