Abstract
Smoking is a major potential risk that could affect variety of organs. In smokers, the pattern of inflammatory process as evaluated by circulating levels of C-reactive protein is associated with a higher risk of CVD and cancer. There are limited local data about the effect of cigarette smoking on the serum levels of HS-CRP. Therefore, the study aimed to estimate of level of serum HS-CRP in Sudanese healthy Cigarette smoker.Blood samples collected from75 Sudanese healthy cigarette smokers and 75 apparently healthy individual nonsmokers as control group recruited in period from January to August 2019. Serum HS-CRP was estimated by Fine careTM data were analyzed using SPSS version 20.The mean of Serum HS-CRP in case and control group was (2.7mg/L +/- 1.3, and 0.16mg/L +/- 0.4) respectively, P value (0.002).The mean of serum HS-CRP among case group according to age from 18-27 was (2.0mg/L +/- 0.8), while the of age from 28-45 was (3.9 mg/L +/- 1.1). serum level of HS-CRP protein was statistically significant twice high in smokers who smoked for more than 8 and less than 24 years P value (0.00).The mean level of Serum HS-CRP is statistically significant elevated in healthy cigarette smokers in compared to non-smokers. There is significant positive correlation between serum HS-CRP with the duration of cigarette smokers as well as advance age; this is because the dangerous chemicals in cigarettes negatively affect the immune, respiratory, and circulatory systems.