Abstract
Detailed study of mild and advanced cases of pregnancy toxaemia was carried out on 39 affected goats. Total fifteen of these goats were diagnosed as mild cases of the disease, whereas 24 of them were considered as advanced cases. The estimation of blood glucose, plasma protein, lactate, pyruvate, Creatine Kinase (CK), Lactate Dehydrogenase (LDH), Aspartate Aminotransferase (AST) and urea nitrogen was carried out. The results were compared with those obtained from healthy pregnant goats. The blood glucose level was low in affected goats. However, plasma lactate, pyruvate, urea nitrogen concentration and creatine kinase and aspartate aminotransferase activities in the same goats were highly increased. These results suggest that the main cause of death among pregnancy toxaemic goats may be due to hepatorenal dysfunction.