Abstract
Objective: To study the histological pattern of benign and malignant ovarian neoplasms.
Study design: A cross-sectional study.
Duration of study: Two and half years.
Place of study: Departments of Pathology, Fatima Memorial Hospital and Arif laboratory, Hameed Latif Hospital Lahore.
Methods: The study consisted of 150 specimens of ovarian tumors, received fixed in 10% formalin. Haematoxylin and Eosin stained slides were examined to determine the histological type by WHO classification.
Results: Majority of these tumors were benign (74%), border line tumors were < 2% and malignant tumors were 24.33%. Histologically the major categories were surface epithelial tumors 92 (61.33%), germ cell tumors 48 (32%) sex cord stromal tumors 9(6%) and metastatic adenocarcinoma 01 (0.66%). Amongst malignant tumors, the most common category was malignant surface epithelial tumor (67.56%) followed by malignant germ cell tumors (24.32%). Serous cystadenocarcinoma was the most common malignant ovarian tumor and 88% malignant surface tumors were seen in the 5th and 6th decades. All 9 malignant germ cell tumors (100%) occurred in patients below 30 years of age. Serous cystadenoma was most common benign tumor (38.73%) followed by mature cystic teratoma (35.13%). Benign ovarian tumors 60.36%(67/111) were seen in 3rd and 4th decades.
Conclusion: Epithelial tumors are the commonest variety of ovarian tumors followed by Germ cell tumors. There are minor differences from local and western studies.