Abstract
In this study, we are presenting a novel hybrid nanostructure, composed of Co3O4 nanocubes adorned on single-walled carbon nanotubes (SWCNT) for electrochemical and non-enzymatic detection of glucose. The Co3O4/SWCNT nanocomposite was fabricated by simple hydrothermal method, followed by drop casting onto a glassy carbon electrode (GCE). The composition and grain size of as-fabricated nanocomposite was verified by X-ray diffraction, the morphology was studied by scanning electron microscopy and the functional groups were examined by Fourier transform infrared spectroscopy. The electrochemical and electrocatalytic behaviors of Co3O4/SWCNT based GC electrodes toward glucose were estimated by cyclic voltannnnograms, electrochemical impedance spectroscopy, and a nnperonnetric methods, respectively. This Co3O4/SWCNT/GCE biosensing device demonstrated higher electrocatalytic activity for the electro-oxidation of glucose in the alkaline media, which furthermore proved to be strongly dependent on NaOH concentration. Our Co3O4/SWCNT/GCE biosensor showed a linear response from 1 to 5 mM with a sensitivity of 96.92 mu A nnM(-1) cm(-1) and limit of detection of 0.25 mu M. Besides, it showed higher selectivity (7-14 times) for glucose against various interfering species including dopamine, ascorbic acid, NaCl, urea and uric acid. Based on these findings, we can foretell potential field applications of this Co3O4/SWCNT/GCE fabricated biosensor for sensitive and selective non-enzymatic estimation of glucose.
[GRAPHICS]
.